Description

3'-Acetyl-3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzanilide is a specialized nitrogen mustard derivative, a class of compounds known for their alkylating properties and significant role in research and development. This compound matters as a crucial building block and reference standard in the synthesis and study of targeted therapeutic agents, particularly in oncology research. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel chemotherapeutic candidates and studying DNA alkylation mechanisms.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of nitrogen mustard-based chemotherapeutic agents and prodrugs.
• Biochemical Research: Used as a reference standard and active agent in studies investigating DNA cross-linking, alkylation mechanisms, and cytotoxicity.
• Oncology Drug Discovery: Serves as a critical scaffold for designing and synthesizing novel targeted cancer therapies in preclinical research.
• Academic Research: Employed in university and institutional labs for fundamental studies on the chemistry and biology of alkylating agents.
• Fine Chemical Synthesis: Utilized as a specialized building block for constructing complex molecules with potential biological activity.
• Reference Material: Supplied as a high-purity compound for analytical method development, validation, and quality control in related API manufacturing.

Basic Information

Item	Details
Product Name	3'-Acetyl-3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzanilide
CAS No.	70020-65-4
Molecular Formula	C21H24Cl2N2O2
Molecular Weight	407.33 g/mol
Synonyms	3'-Acetyl-3-[bis(2-chloroethyl)amino]-4-methylbenzanilide; 4'-Acetyl-3-[bis(2-chloroethyl)amino]-2-methylbenzanilide; Benzanilide, 3'-acetyl-3-[bis(2-chloroethyl)amino]-4-methyl-; Nitrogen mustard benzanilide derivative; Chlorambucil anilide analog; Contact for details on EINECS.

Quality Control

Our 3'-Acetyl-3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.