Description

(3As)-3,3Aβ,4,5,9Aβ,9Bα-Hexahydro-9-(Hydroxymethyl)-3β,6-Dimethylazuleno[4,5-B]Furan-2,7-Dione is a high-purity, complex sesquiterpene lactone derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chiral building block and a potential precursor for developing novel bioactive molecules with targeted therapeutic properties. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for anti-inflammatory or anticancer agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of novel small-molecule drug candidates.
• Natural Product Synthesis: Acts as a critical intermediate in the total or semi-synthesis of complex sesquiterpenoids and related natural products.
• Biochemical Research: Employed as a reference standard or probe compound in biochemical assays to study specific enzymatic pathways or biological targets.
• Fine Chemical Synthesis: Utilized in the preparation of specialty chemicals, advanced materials, and other high-value derivatives requiring a complex, functionalized molecular framework.

Basic Information

Product Name	(3As)-3,3Aβ,4,5,9Aβ,9Bα-Hexahydro-9-(Hydroxymethyl)-3β,6-Dimethylazuleno[4,5-B]Furan-2,7-Dione
CAS No.	7726-34-3
Molecular Formula	C15H18O4
Molecular Weight	262.30 g/mol
Synonyms	9-Hydroxymethyl-3β,6-dimethyldihydrocostunolide; Dihydrocostunolide derivative; Azuleno[4,5-b]furan-2,7-dione, hexahydro-9-(hydroxymethyl)-3β,6-dimethyl-, (3aR,3bS,4S,7aS,8S,8aR)-rel-; (rel-(3aR,3bS,4S,7aS,8S,8aR))-Octahydro-8-(hydroxymethyl)-3b,6-dimethylazuleno[4,5-b]furan-2,7-dione; A sesquiterpene lactone alcohol
EINECS	Contact for details

Quality Control

Our (3As)-3,3Aβ,4,5,9Aβ,9Bα-Hexahydro-9-(Hydroxymethyl)-3β,6-Dimethylazuleno[4,5-B]Furan-2,7-Dione is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); for long-term storage, consider packaging under an inert gas such as nitrogen or argon in a sealed container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.