Description

(E)-3-(4-Methoxy-Phenyl)-But-2-Enoic Acid Ethyl Ester is a high-purity, versatile α,β-unsaturated ester building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and fine chemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing specific molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing a chalcone or cinnamate core structure.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive alkene functionality.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring the (E)-configured α,β-unsaturated ester moiety.
• Organic Synthesis Research: Employed in academic and industrial labs for Michael addition reactions, cyclization studies, and as a dienophile in Diels-Alder reactions.
• Material Science Precursor: Investigated for use in the synthesis of organic semiconductors and photoactive polymers due to its conjugated system.

Basic Information

Product Name	(E)-3-(4-Methoxy-Phenyl)-But-2-Enoic Acid Ethyl Ester
CAS No.	7706-82-3
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	Ethyl (E)-3-(4-Methoxyphenyl)but-2-enoate; (E)-Ethyl 3-(4-Methoxyphenyl)-2-butenoate; Ethyl 4-Methoxy-β-methylcinnamate; (E)-Ethyl 4-Methoxy-β-methylcinnamate; 2-Butenoic acid, 3-(4-methoxyphenyl)-, ethyl ester, (E)-; Ethyl (E)-3-(p-Methoxyphenyl)but-2-enoate; p-Methoxy-β-methylcinnamic acid ethyl ester
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Methoxy-Phenyl)-But-2-Enoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
(E)-Isomer Content (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.