Description

2,6-Bis(Bromomethyl)Pyridine is a versatile and highly reactive brominated pyridine derivative, serving as a critical bifunctional alkylating agent and a key synthetic intermediate. Its value lies in its ability to introduce two reactive bromomethyl groups into molecular frameworks, enabling the construction of complex heterocyclic systems and functionalized ligands. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs), catalysts, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing complex drug molecules, particularly in the development of kinase inhibitors and other nitrogen-containing heterocyclic APIs.
• Ligand Synthesis: Used to prepare polydentate nitrogen ligands for coordination chemistry and catalysis, including pincer-type ligands for transition metal complexes.
• Polymer & Material Science: Acts as a cross-linking agent or monomer precursor for creating functional polymers, dendrimers, and supramolecular structures.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators that utilize pyridine-based scaffolds.
• Chemical Cross-linking: Utilized in protein modification studies and the preparation of affinity chromatography media due to its reactive bromomethyl groups.
• Organic Synthesis: Serves as a versatile precursor for further functionalization via nucleophilic substitution reactions to create a wide array of 2,6-disubstituted pyridine derivatives.

Basic Information

Product Name	2,6-Bis(Bromomethyl)Pyridine
CAS No.	7703-74-4
Molecular Formula	C7H7Br2N
Molecular Weight	264.95 g/mol
Synonyms	2,6-Bis(bromomethyl)pyridine; 2,6-Di(bromomethyl)pyridine; Pyridine, 2,6-bis(bromomethyl)-; 2,6-Pyridinedimethanol, dibromide; 2,6-Dibromomethylpyridine; α,α'-Dibromo-2,6-lutidine; 2,6-Bis(bromylmethyl)pyridine
EINECS	231-724-9

Quality Control

Our 2,6-Bis(Bromomethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.