Description

16-Methylene Estradiol is a synthetic steroidal estrogen derivative, recognized for its potent biological activity. This compound is a critical intermediate in the synthesis of more complex steroidal pharmaceuticals and is valued for its role in advanced research and development. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in hormone-related therapeutic development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of steroidal drugs and novel estrogen receptor modulators.
• Biochemical Research: Used as a reference standard and active compound in studies of estrogenic activity, receptor binding, and metabolic pathways.
• Hormone Analog Development: Serves as a precursor for creating analogs with modified pharmacological profiles for therapeutic applications.
• Academic & Institutional Research: Employed in university and institutional labs for endocrinology and medicinal chemistry projects.
• Fine Chemical Synthesis: Integrated into multi-step synthetic routes for producing high-value, complex organic molecules.

Basic Information

Product Name	16-Methylene Estradiol
CAS No.	7627-87-4
Molecular Formula	C19H24O2
Molecular Weight	284.39 g/mol
Synonyms	16-Methyleneestra-1,3,5(10)-triene-3,17β-diol; 16-Methylene-17β-estradiol; 16-Methylenestra-1,3,5(10)-triene-3,17β-diol; Estra-1,3,5(10)-triene-3,17-diol, 16-methylene-, (17β)-; 16-Methylene-E2
EINECS	Contact for details

Quality Control

Our 16-Methylene Estradiol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.