Description

3β-(Triethylsiloxy)Cholest-5-Ene is a high-purity, protected steroid intermediate, specifically a cholestane derivative with a triethylsilyl (TES) ether group at the 3β-position. This compound is critical for advanced organic synthesis, particularly in the pharmaceutical and research sectors, where it serves as a versatile building block for the preparation of complex steroidal molecules. Key industries that rely on this intermediate include pharmaceutical R&D, fine chemical manufacturing, and academic research laboratories focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key protected precursor in the multi-step synthesis of novel steroid-based therapeutics, including hormone modulators and anti-inflammatory agents.
• Research & Development: Used in academic and industrial R&D for studying steroid biosynthesis pathways, receptor interactions, and metabolic processes.
• Fine Chemical Synthesis: Serves as a specialized starting material or intermediate for producing high-value, custom steroidal compounds and reference standards.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for steroidal active pharmaceutical ingredients (APIs) under controlled conditions.

Basic Information

Product Name	3β-(Triethylsiloxy)Cholest-5-Ene
CAS No.	7604-85-5
Molecular Formula	C₃₃H₆₀OSi
Molecular Weight	512.92 g/mol
Synonyms	Cholest-5-en-3β-ol, 3-(triethylsilyl) ether; 3β-Triethylsiloxycholest-5-ene; 3-Triethylsilyloxycholest-5-ene; 5-Cholesten-3β-ol, triethylsilyl ether; TES-Cholesterol; (3β)-Cholest-5-en-3-yloxy-triethylsilane; Triethylsilyl cholesterol ether; 3β-Hydroxy-5-cholestene triethylsilyl ether
EINECS	Contact for details

Quality Control

Our 3β-(Triethylsiloxy)Cholest-5-Ene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. We adhere to current Good Manufacturing Practices (cGMP) where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and research customers. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.