Description

3-Chloro-N,N-Bis(trimethylsilyl)aniline is a specialized organosilicon reagent featuring a protected aniline nitrogen. This compound matters for its role as a versatile synthetic intermediate, offering enhanced stability and reactivity for advanced organic transformations. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring chlorinated aromatic amines.
• Advanced Material Precursor: Serves as a monomer or functionalization agent for silicon-containing polymers and specialty resins.
• Organic Synthesis Reagent: Acts as a protected aniline equivalent in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination).
• Semiconductor & Electronics: Potential use in chemical vapor deposition (CVD) processes for depositing silicon-nitrogen thin films.
• Research & Development: Valuable tool for academic and industrial R&D in medicinal chemistry and organometallic catalysis.

Basic Information

Product Name	3-Chloro-N,N-Bis(trimethylsilyl)aniline
CAS No.	7522-27-2
Molecular Formula	C12H22ClNSi2
Molecular Weight	271.94 g/mol
Synonyms	N,N-Bis(trimethylsilyl)-3-chloroaniline; 3-Chloro-N,N-bis(trimethylsilyl)benzenamine; 3-Chloro-N,N-di(trimethylsilyl)aniline; Benzenamine, 3-chloro-N,N-bis(trimethylsilyl)-; 3-Chloro-N,N-bis(trimethylsilyl)phenylamine; TMS-protected 3-chloroaniline; BTSA derivative
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-N,N-Bis(trimethylsilyl)aniline adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. All materials are characterized by modern analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.