Description

Proline, 5-Oxo-, 2-Hydroxyethyl Ester (7Ci,8Ci) is a specialized proline derivative, also known as 5-oxoproline 2-hydroxyethyl ester, with the CAS registry number 7518-82-3. This compound serves as a versatile chiral building block and intermediate for the synthesis of more complex molecules, offering significant value in fine chemical and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in peptide mimetics, prodrug development, and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for prodrug strategies and peptide-based therapeutics.
• Agrochemical Synthesis: Used as a building block for creating advanced, optically active crop protection agents and herbicides.
• Biochemical Research: Employed in proteomics and enzymology studies as a substrate analog or inhibitor to investigate metabolic pathways involving proline and glutamic acid.
• Fine Chemical Production: Serves as a precursor in the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Cosmetic Ingredient Intermediate: Potential use in the synthesis of novel moisturizing or anti-aging compounds, such as peptide derivatives for skincare formulations.
• Academic & Industrial R&D: A valuable reagent for method development in organic synthesis, catalysis research, and exploring new chemical entities.

Basic Information

Product Name	Proline, 5-Oxo-, 2-Hydroxyethyl Ester (7Ci,8Ci)
CAS No.	7518-82-3
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	5-Oxoproline 2-Hydroxyethyl Ester; L-Pyroglutamic Acid 2-Hydroxyethyl Ester; 2-Hydroxyethyl 5-Oxo-L-prolinate; 5-Oxo-L-proline 2-Hydroxyethyl Ester; Ethylene Glycol Monoester of 5-Oxoproline; Pyroglutamic Acid Hydroxyethyl Ester; 2-(5-Oxo-L-prolyloxy)ethanol; (S)-2-(5-Oxopyrrolidine-2-carboxyloxy)ethanol
EINECS	Contact for details

Quality Control

Our Proline, 5-Oxo-, 2-Hydroxyethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.