Description

Methyl-6-o-Trityl-2,3,4-Tri-o-Acetyl-α-D-Mannopyranoside is a key protected carbohydrate intermediate, specifically a mannose derivative with orthogonal protecting groups. This compound is essential for synthetic chemists requiring precise control over glycosylation reactions and the selective manipulation of sugar hydroxyl groups. It is primarily used in the research and development of complex oligosaccharides, glycoconjugates, and novel pharmaceuticals, serving the needs of advanced organic synthesis and medicinal chemistry laboratories.

Application

• Glycoscience Research: A critical building block for the chemical and enzymatic synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Development: Used as a key intermediate in the synthesis of carbohydrate-based drug candidates, vaccines, and diagnostic agents.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by allowing selective deprotection and functionalization at specific positions on the mannose ring.
• Glycoconjugate Synthesis: Serves as a precursor for creating glycopeptides, glycolipids, and other biologically active conjugates.
• Chemical Biology Probes: Utilized in the development of labeled sugars and inhibitors for studying carbohydrate-processing enzymes and pathways.
• Process Chemistry: Acts as a standardized intermediate for scaling up the production of carbohydrate-active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Methyl-6-o-Trityl-2,3,4-Tri-o-Acetyl-α-D-Mannopyranoside
CAS No.	7511-40-2
Molecular Formula	C36H38O9
Molecular Weight	614.68 g/mol
Synonyms	Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-mannopyranoside; α-D-Mannopyranoside, methyl 6-O-triphenylmethyl-2,3,4-tri-O-acetate; Methyl 2,3,4-Tri-O-acetyl-6-O-trityl-α-D-mannopyranoside; 6-O-Trityl-2,3,4-Tri-O-acetyl-α-D-methylmannoside; Protected α-Methyl D-Mannoside; Trityl-protected Mannose Derivative
EINECS	Contact for details

Quality Control

Every batch of Methyl-6-o-Trityl-2,3,4-Tri-o-Acetyl-α-D-Mannopyranoside is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical synthetic applications. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.