Description

2-Chloro-3-Nitro-5-Pyridinecarboxylic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular construction. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Used to create novel pyridine-based ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Intermediate for synthesizing functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and diagnostic agents in biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Chloro-3-Nitro-5-Pyridinecarboxylic Acid
CAS No.	7477-10-3
Molecular Formula	C6H3ClN2O4
Molecular Weight	202.55 g/mol
Synonyms	5-Carboxy-2-chloro-3-nitropyridine; 2-Chloro-3-nitro-5-pyridinecarboxylic acid; 3-Nitro-2-chloropyridine-5-carboxylic acid; 2-Chloro-3-nitropyridine-5-carboxylic acid; 2-Chloro-3-nitro-5-pyridine carboxylic acid; 2-Chloro-3-nitroisonicotinic acid; 2-Chloro-3-nitro-5-carboxypyridine; 2-Chloro-3-nitro-5-pyridylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Nitro-5-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.