Description

4-(Trimethylsilyl)Cyclohexanone is a versatile organosilicon building block characterized by its ketone functionality protected by a trimethylsilyl group. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the production of complex molecules where the silyl group acts as a protective or directing moiety. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially in medicinal chemistry research for creating complex heterocycles and chiral molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators where the silyl group aids in specific chemical transformations.
• Organometallic Chemistry: Serves as a ligand precursor or a substrate in reactions involving silicon-mediated bond formations and catalytic processes.
• Material Science Research: Employed in the development of silicon-containing polymers, resins, and advanced coatings with tailored properties.
• Flavor & Fragrance Industry: Acts as an intermediate for synthesizing specific musk compounds and other complex aroma chemicals.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, including new silylation and desilylation protocols.

Basic Information

Product Name	4-(Trimethylsilyl)Cyclohexanone
CAS No.	7452-95-1
Molecular Formula	C9H18OSi
Molecular Weight	170.32 g/mol
Synonyms	4-Trimethylsilylcyclohexanone; Cyclohexanone, 4-(trimethylsilyl)-; 4-TMS-cyclohexanone; (4-Oxocyclohexyl)trimethylsilane; Trimethyl(4-oxocyclohexyl)silane; NSC 163082
EINECS	Contact for details

Quality Control

Our 4-(Trimethylsilyl)Cyclohexanone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing the exact specifications of your order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.