Description

5-Isobutyl-1,3-Dimethylbarbituric Acid is a specialized barbiturate derivative, a class of compounds historically significant in medicinal chemistry. This high-purity intermediate is valued for its precise molecular structure, which serves as a critical building block in advanced organic synthesis. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, fine chemical synthesis, and method validation studies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new chemical entities and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and method development for HPLC, GC, and other chromatographic techniques.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of barbiturate-related compounds and their biological interactions.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct more elaborate molecular architectures for specialty chemicals.

Basic Information

Product Name	5-Isobutyl-1,3-Dimethylbarbituric Acid
CAS No.	7435-61-2
Molecular Formula	C10H16N2O3
Molecular Weight	212.25 g/mol
Synonyms	1,3-Dimethyl-5-(2-methylpropyl)barbituric Acid; 5-(2-Methylpropyl)-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 1,3-Dimethyl-5-isobutylbarbituric Acid; 5-Isobutyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione; NSC 5239; Isobutylmethylbarbituric Acid Derivative
EINECS	Contact for details

Quality Control

Our 5-Isobutyl-1,3-Dimethylbarbituric Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including identity confirmation (IR, NMR), purity assay (HPLC), and impurity profiling to ensure it meets the stringent requirements for research and development use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.