Description

Methyl Bromopyruvate is a versatile and highly reactive brominated ester, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce both a bromine atom and a reactive carbonyl group, enabling efficient carbon-carbon bond formation and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize complex molecules, active pharmaceutical ingredients (APIs), and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring bromoalkyl or α-keto ester motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its reactivity to create complex molecular structures.
• Peptide Mimetics & Bioconjugation: Employed in the preparation of peptide analogs and for bioconjugation chemistry, where it acts as an electrophilic linker.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex organic frameworks.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and molecular tags for studying enzyme function and protein interactions.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialized polymers and advanced materials.

Basic Information

Product Name	Methyl Bromopyruvate
CAS No.	7425-63-0
Molecular Formula	C4H5BrO3
Molecular Weight	181.99 g/mol
Synonyms	Methyl 3-bromo-2-oxopropanoate; 3-Bromopyruvic acid methyl ester; Bromopyruvic acid methyl ester; 2-Oxopropyl bromoacetate; Methyl α-bromopyruvate; Methyl bromopyruvate ester; Bromomethyl pyruvate; Methyl ester of bromopyruvic acid
EINECS	231-058-4

Quality Control

Our Methyl Bromopyruvate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and manufacturing use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.