Description

Trimethylsilyl Dihydrogen Phosphate is a versatile organosilicon reagent primarily used as a silylating agent and a key intermediate in organic synthesis. This compound is valued for its ability to introduce the trimethylsilyl group, protecting reactive sites and modifying the properties of target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for nucleotide and phosphate ester analogs.
• Silylating Agent: Used to protect hydroxyl and other labile functional groups in multi-step organic synthesis, improving reaction selectivity and yield.
• Polymer Chemistry: Serves as a monomer or modifier in the production of specialty silicones and phosphate-containing polymers.
• Agrochemical Synthesis: Employed as an intermediate in the manufacture of certain herbicides, insecticides, and plant growth regulators.
• Surface Modification: Used to treat inorganic surfaces like silica or glass to alter their hydrophobicity and reactivity.
• Laboratory Research: A valuable reagent in academic and industrial R&D for developing new synthetic methodologies and materials.

Basic Information

Product Name	Trimethylsilyl Dihydrogen Phosphate
CAS No.	7422-66-4
Molecular Formula	C3H11O4PSi
Molecular Weight	170.18 g/mol
Synonyms	Dihydrogen Trimethylsilyl Phosphate; Phosphoric Acid Trimethylsilyl Ester; Trimethylsilyl Phosphate; (Trimethylsilyl) Dihydrogen Phosphate; TMS-Dihydrogen Phosphate; TMSP; Trimethylsiloxyphosphonic Acid; O-Trimethylsilyl Dihydrogen Phosphate
EINECS	231-047-7

Quality Control

Our Trimethylsilyl Dihydrogen Phosphate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from GC, NMR, and titration methods. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Chloride (as Cl)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.