Description

4-Chloropyridine-3-Carboxamide is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both a chloro substituent and a carboxamide group on the pyridine ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functional organic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a functionalized chloropyridine derivative.

Basic Information

Product Name	4-Chloropyridine-3-Carboxamide
CAS No.	7418-70-4
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	3-Carbamoyl-4-chloropyridine; 4-Chloro-3-pyridinecarboxamide; 4-Chloronicotinamide; 4-Chloropyridine-3-carboxylic acid amide; 4-Chloro-3-pyridinecarboxylic acid amide; 4-Chloro-3-pyridylcarboxamide; 4-Chloronicotinic acid amide
EINECS	Contact for details

Quality Control

Every batch of 4-Chloropyridine-3-Carboxamide is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA), including results for identity, purity, and impurity profiles (typically by HPLC), is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.