Description

2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl Azide is a key protected ribofuranosyl intermediate used in nucleoside and nucleotide synthesis. This compound matters for its role as a versatile glycosyl donor and precursor in the production of modified nucleosides, which are critical for pharmaceutical research and development. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical industries for the synthesis of antiviral agents, anticancer drugs, and other bioactive molecules.

Application

• Nucleoside Synthesis: A crucial glycosyl donor for the convergent synthesis of modified nucleosides and nucleotides.
• Pharmaceutical Intermediates: Serves as a key building block in the production of antiviral and anticancer drug candidates.
• Oligonucleotide Chemistry: Used in the preparation of sugar-modified oligonucleotides for antisense and siRNA therapeutics.
• Carbohydrate Chemistry Research: An important reagent for studying glycosylation reactions and protecting group strategies.
• Prodrug Development: Employed in the design and synthesis of nucleoside prodrugs to enhance bioavailability.
• Agrochemical Research: Potential use as an intermediate in the synthesis of novel nucleoside-based pesticides or plant growth regulators.

Basic Information

Product Name	2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl Azide
CAS No.	7408-41-5
Molecular Formula	C26H21N3O7
Molecular Weight	487.46 g/mol
Synonyms	1-Azido-2,3,5-tri-O-benzoyl-β-D-ribofuranose; 2,3,5-Tri-O-benzoyl-D-ribofuranosyl azide; β-D-Ribofuranosyl azide, 2,3,5-tribenzoate; 1-Azido-1-deoxy-2,3,5-tri-O-benzoyl-β-D-ribofuranose; Tribenzoyl ribofuranosyl azide; Azido tribenzoyl ribofuranoside
EINECS	Contact for details

Quality Control

Our 2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl Azide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, well-ventilated place. Keep away from heat, sparks, and open flame. Due to its light-sensitive and easily oxidized nature, prolonged exposure to light and air should be strictly avoided.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.