Description

2,3,5-Tri-o-Benzoyl-2-C-Methyl-D-Ribonic Acid-1,4-Lactone is a key protected sugar lactone derivative, serving as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. Its value lies in providing a sterically hindered, enantiomerically pure scaffold for constructing complex nucleoside analogs and other bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for API synthesis and process development.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery programs.
• Chiral Building Block: Used in asymmetric synthesis to introduce the 2-C-methyl-D-ribonolactone moiety into complex target molecules, leveraging its defined stereochemistry.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs) requiring protected sugar intermediates.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to carbohydrate metabolism and nucleoside-processing enzymes.
• Fine Chemical Synthesis: Utilized for preparing specialized ligands, catalysts, or molecular probes where a rigid, benzoylated sugar framework is advantageous.

Basic Information

Product Name	2,3,5-Tri-o-Benzoyl-2-C-Methyl-D-Ribonic Acid-1,4-Lactone
CAS No.	7392-74-7
Molecular Formula	C28H22O8
Molecular Weight	486.47 g/mol
Synonyms	2-C-Methyl-D-ribono-1,4-lactone 2,3,5-tribenzoate; 2,3,5-Tri-O-benzoyl-2-C-methyl-D-ribono-1,4-lactone; 2-C-Methyl-D-ribonolactone tribenzoate; 2,3,5-Tribenzoyl-2-C-methyl-D-ribono-γ-lactone; 2-C-Methyl-D-ribono-1,4-lactone tri-O-benzoate; 2-C-Methylribono-1,4-lactone 2,3,5-tribenzoate
EINECS	Contact for details

Quality Control

Our 2,3,5-Tri-o-Benzoyl-2-C-Methyl-D-Ribonic Acid-1,4-Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.