Description

1,3-Dimethyl-5-Phenylbarbituric Acid is a specialized barbiturate derivative with a phenyl substituent at the 5-position. This compound serves as a crucial pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of barbiturate-based active pharmaceutical ingredients (APIs) and other central nervous system (CNS) agents.
• Organic Synthesis Building Block: Utilized in research and development for constructing complex heterocyclic compounds and novel molecular entities.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Research & Development: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new therapeutic candidates.

Basic Information

Product Name	1,3-Dimethyl-5-Phenylbarbituric Acid
CAS No.	7391-66-4
Molecular Formula	C₁₂H₁₂N₂O₃
Molecular Weight	232.24 g/mol
Synonyms	5-Phenyl-1,3-dimethylbarbituric Acid; 1,3-Dimethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Phenyl-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; NSC 406130; Dimethylphenylbarbituric Acid; 1,3-Dimethyl-5-phenylbarbituric acid
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-5-Phenylbarbituric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications, including assay by HPLC, related substances, and residual solvents, to support your regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.