Description

1,2-Bis(Trimethylsilyloxy)Ethane is a versatile organosilicon compound, primarily valued as a key silylating agent and protecting group reagent in synthetic organic chemistry. Its core function is to introduce trimethylsilyl (TMS) groups, effectively protecting reactive hydroxyl functionalities and modifying compound solubility. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate Synthesis: Used as a protecting group for diols and polyols during the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the manufacture of pesticides and herbicides where silylation is required to control reactivity and improve process yields.
• Silylating Agent for Gas Chromatography (GC): Derivatives polar compounds (e.g., sugars, alcohols) to increase their volatility and thermal stability for accurate GC analysis.
• Polymer & Silicone Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialized silicone-based polymers and materials.
• Organic Synthesis Reagent: Protects hydroxyl groups in sensitive reactions, enabling selective transformations in complex molecule construction.
• Laboratory Research & Development: A fundamental reagent for chemists in R&D settings exploring new synthetic pathways and compound libraries.

Basic Information

Product Name	1,2-Bis(Trimethylsilyloxy)Ethane
CAS No.	7381-30-8
Molecular Formula	C8H22O2Si2
Molecular Weight	206.43 g/mol
Synonyms	Ethylene Glycol Bis(trimethylsilyl) Ether; 1,2-Ethanediol, 1,2-bis(trimethylsilyl) ether; Bis(trimethylsilyl) Ethylene Glycol; Ethane-1,2-diyl bis(oxy(trimethyl)silane); Glycol Bis(trimethylsilyl) Ether; TMS Glycol Ether; 1,2-Bis(trimethylsiloxy)ethane
EINECS	230-964-3

Quality Control

Our 1,2-Bis(Trimethylsilyloxy)Ethane is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including GC (Gas Chromatography) and NMR (Nuclear Magnetic Resonance) spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and highly volatile; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.