Description

(S)-(+)-o-Acetyl-L-Mandelic Acid is a high-purity, single-enantiomer chiral building block and intermediate of significant importance in asymmetric synthesis. This compound is valued for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Used as a resolving agent or a chiral auxiliary in stereoselective chemical reactions to induce desired chirality in target molecules.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological development in organic and medicinal chemistry.
• Catalyst Ligand Synthesis: A potential precursor for synthesizing chiral ligands used in homogeneous catalysis.

Basic Information

Product Name	(S)-(+)-o-Acetyl-L-Mandelic Acid
CAS No.	7322-88-5
Molecular Formula	C10H10O5
Molecular Weight	210.18 g/mol
Synonyms	(S)-2-Acetoxy-2-phenylacetic Acid; (S)-(+)-2-Acetoxy-2-phenylacetic Acid; L-(+)-O-Acetylmandelic Acid; (S)-O-Acetylmandelic Acid; (S)-α-Acetoxyphenylacetic Acid; (2S)-2-Acetoxy-2-phenylacetic Acid; (S)-(+)-α-Acetoxyphenylacetic Acid; Acetyl-L-mandelic Acid
EINECS	Contact for details

Quality Control

Our (S)-(+)-o-Acetyl-L-Mandelic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, consistent with standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.