Description

n-Methoxy-α,α,α-Trimethyl-n-(Trimethylsilyl)Silanamine is a highly reactive organosilicon compound, primarily valued as a versatile silylating and protecting agent in advanced organic synthesis. Its core function is to introduce the trimethylsilyl (TMS) group, which is crucial for modifying the reactivity and solubility of target molecules. This specialty chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise control over molecular structure during complex synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key reagent for protecting sensitive functional groups, such as amines and alcohols, during the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the manufacture of advanced pesticides and herbicides where silylation steps are required to achieve desired biological activity and stability.
• Advanced Material Development: Serves as a precursor or modifying agent in the synthesis of specialty silicones, silicon-based polymers, and surface-modifying coatings.
• Analytical Chemistry: Utilized to derivative compounds for Gas Chromatography-Mass Spectrometry (GC-MS) analysis, improving volatility and detection of polar molecules.
• Organic Synthesis Reagent: Acts as a strong base and nucleophile in various condensation, elimination, and substitution reactions to construct complex molecular architectures.

Basic Information

Product Name	n-Methoxy-α,α,α-Trimethyl-n-(Trimethylsilyl)Silanamine
CAS No.	7266-76-4
Molecular Formula	C7H21NOSi2
Molecular Weight	191.42 g/mol
Synonyms	Methoxy(trimethylsilyl)aminotrimethylsilane; (Methoxy(trimethylsilyl)amino)trimethylsilane; N-Methoxy-N-(trimethylsilyl)trimethylsilylamine; Hexamethyldisilazane, N-methoxy-; N-(Methoxy)hexamethyldisilazane; HMDS, N-methoxy derivative; Bis(trimethylsilyl)methoxyamine
EINECS	Contact for details

Quality Control

Our n-Methoxy-α,α,α-Trimethyl-n-(Trimethylsilyl)Silanamine is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for traceability and reliable supply to critical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.