Description

Dimethyl 3-Hydroxyglutarate is a high-purity diester derivative of 3-hydroxyglutaric acid, serving as a versatile and valuable chiral building block in advanced organic synthesis. Its significance lies in its bifunctional structure, featuring both ester and hydroxyl groups, which allows for selective transformations and incorporation into complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), fine chemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of statin drugs, bioactive molecules, and other complex APIs requiring precise stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating biodegradable polymers, polyesters, and specialty resins.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals.
• Organic Synthesis Reagent: Utilized in asymmetric synthesis, Michael additions, and other carbon-carbon bond-forming reactions in R&D laboratories.
• Biochemical Research: Employed in metabolic pathway studies and as a standard or reagent in enzymatic assays.

Basic Information

Product Name	Dimethyl 3-Hydroxyglutarate
CAS No.	7250-55-7
Molecular Formula	C7H12O5
Molecular Weight	176.17 g/mol
Synonyms	3-Hydroxyglutaric Acid Dimethyl Ester; Dimethyl 3-Hydroxypentanedioate; Methyl 3-Hydroxyglutarate; 3-Hydroxy-1,5-pentanedioic Acid Dimethyl Ester; Pentanedioic acid, 3-hydroxy-, 1,5-dimethyl ester; Glutaric acid, 3-hydroxy-, dimethyl ester
EINECS	Contact for details

Quality Control

Our Dimethyl 3-Hydroxyglutarate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.