Description

4-Pyridinecarboxaldehyde n-Oxide is a versatile heterocyclic building block and key intermediate in organic synthesis. This compound is valued for its unique reactivity as an N-oxide, which activates the pyridine ring towards nucleophilic substitution and facilitates the synthesis of complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those containing functionalized pyridine or pyridine N-oxide moieties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the N-oxide group modifies bioactivity and selectivity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chiral and achiral ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the creation of organic semiconductors, metal-organic frameworks (MOFs), and other functional polymers.
• Chemical Research & Development: A fundamental reagent for method development, exploring new organic reactions, and synthesizing complex heterocyclic systems.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, dyes, and photographic chemicals.

Basic Information

Product Name	4-Pyridinecarboxaldehyde n-Oxide
CAS No.	7216-42-4
Molecular Formula	C6H5NO2
Molecular Weight	123.11 g/mol
Synonyms	4-Formylpyridine N-Oxide; 4-Pyridinecarboxaldehyde 1-Oxide; 4-Pyridylaldehyde N-Oxide; Isonicotinaldehyde N-Oxide; Pyridine-4-carboxaldehyde N-Oxide; 4-Pyridinealdehyde N-Oxide; 4-Pyridinecarboxaldehyde 1-Oxide; 4-Pyridinecarboxaldehyde, N-oxide
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxaldehyde n-Oxide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize repeated exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.