Description

2-Pyridinecarboxaldehyde, 1-Oxide is a versatile heterocyclic building block and key synthetic intermediate. Its value lies in its unique N-oxide functionality, which activates the pyridine ring for electrophilic substitution and serves as a directing group in metal-catalyzed cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing functionalized pyridine or bipyridine cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands used in homogeneous catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Derivatization: The aldehyde group allows for further functionalization via condensation, reduction, or Grignard reactions to create diverse chemical libraries.

Basic Information

Product Name	2-Pyridinecarboxaldehyde, 1-Oxide
CAS No.	7216-40-2
Molecular Formula	C6H5NO2
Molecular Weight	123.11 g/mol
Synonyms	Picolinaldehyde N-Oxide; 2-Formylpyridine N-Oxide; 2-Pyridinecarboxaldehyde N-Oxide; 2-Pyridylaldehyde N-Oxide; Picolinaldehyde 1-Oxide; 1-Oxido-2-pyridinecarboxaldehyde; 2-Pyridinealdehyde N-Oxide; α-Pyridylaldehyde N-Oxide
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxaldehyde, 1-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity, it is recommended to store the material under an inert atmosphere to prevent oxidation and minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.