Description

3,5-Diiodo-4-Hydroxypyridine is a halogenated pyridine derivative characterized by its two iodine atoms and hydroxyl group, which make it a valuable synthetic intermediate. This compound matters for its role in constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as API synthesis and the creation of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting thyroid function or requiring iodine-containing motifs.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the diiodo-substitution can influence biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials and liquid crystals due to its halogenated aromatic structure.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form more complex biaryl systems.

Basic Information

Product Name	3,5-Diiodo-4-Hydroxypyridine
CAS No.	7153-08-4
Molecular Formula	C5H3I2NO
Molecular Weight	346.89 g/mol
Synonyms	4-Hydroxy-3,5-diiodopyridine; 3,5-Diiodo-4-pyridinol; 4-Pyridinol, 3,5-diiodo-; DIH; 3,5-Diiodopyridin-4-ol
EINECS	Contact for details

Quality Control

Our 3,5-Diiodo-4-Hydroxypyridine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.