Description

6-[(2Z)-2-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylidene]Hydrazinyl]- 1,3-Dimethyl-Pyrimidine-2,4-Dione is a specialized heterocyclic compound that serves as a critical intermediate in advanced organic synthesis. Its molecular architecture, featuring a pyrimidine-2,4-dione core linked to a nitrogen mustard derivative via a hydrazone bridge, makes it a valuable precursor for developing novel bioactive molecules. This compound is primarily sought by research institutions and pharmaceutical developers focused on medicinal chemistry, particularly in the exploration of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of potential anticancer and alkylating agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop novel small-molecule inhibitors.
• Biochemical Probe Synthesis: Serves as a precursor for creating labeled compounds or probes for biological target identification.
• Organic Synthesis: A versatile intermediate for constructing complex heterocyclic systems in academic and industrial R&D settings.
• Preclinical Development: Employed in the synthesis of candidate compounds for pharmacological evaluation and screening.

Basic Information

Product Name	6-[(2Z)-2-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylidene]Hydrazinyl]- 1,3-Dimethyl-Pyrimidine-2,4-Dione
CAS No.	7150-67-6
Molecular Formula	C₁₇H₂₁Cl₂N₅O₂
Molecular Weight	398.29 g/mol
Synonyms	1,3-Dimethyl-6-[(2Z)-2-[[4-[bis(2-chloroethyl)amino]phenyl]methylene]hydrazinyl]-2,4(1H,3H)-pyrimidinedione; 6-[(2Z)-2-[[4-[Bis(2-chloroethyl)amino]benzylidene]hydrazinyl]-1,3-dimethyluracil; NSC 82196; Uracil mustard hydrazone derivative; 1,3-Dimethyl-6-[(Z)-[4-[bis(2-chloroethyl)amino]phenyl]methylidene]hydrazinyl]pyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure traceability and support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.