Description

Isonicotinic Anhydride is a versatile and reactive organic chemical intermediate, primarily used in the synthesis of more complex molecules. Its value lies in its role as a key building block for creating active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers. This compound is essential for research and development chemists and production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new compounds or optimize synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drugs, particularly those containing the isonicotinoyl moiety, such as certain anti-tuberculosis agents and other therapeutic molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where it acts as a core component for building active ingredients.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in coordination chemistry and homogeneous catalysis.
• Polymer Chemistry: Employed in the creation of functional polymers and polyamides, contributing specific chemical properties to the final material.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical entities and synthetic methodologies.
• Fine Chemical Production: Integral to the manufacture of complex fine chemicals and dyes that require the isonicotinic acid structure.

Basic Information

Product Name	Isonicotinic Anhydride
CAS No.	7082-71-5
Molecular Formula	C12H8N2O3
Molecular Weight	228.20 g/mol
Synonyms	4-Pyridinecarboxylic Anhydride; Isonicotinic Acid Anhydride; Pyridine-4-carboxylic Anhydride; 4-Pyridylcarboxylic Anhydride; 4-Carboxypyridine Anhydride; Disonicotinoyl Anhydride; Disonicotinoyl Oxide
EINECS	230-387-1

Quality Control

Our Isonicotinic Anhydride is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and identification by FT-IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Melting Point	158 - 162 °C
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.