Description

4-(Isocyanatosulfonyl)-Anisole is a specialized aromatic sulfonyl isocyanate derivative, serving as a high-value chemical building block for advanced synthesis. Its core value lies in its dual reactive functionality, enabling the precise introduction of both isocyanate and sulfonyl groups into target molecules. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonylurea and sulfonamide-based drug candidates, particularly in metabolic disease and oncology research.
• Agrochemical Synthesis: Used in creating novel herbicides and pesticides with sulfonyl isocyanate moieties for enhanced activity and selectivity.
• Polymer Modification: Serves as a cross-linking agent or functional monomer to introduce sulfonyl and urethane groups into specialty polymers, improving adhesion, chemical resistance, or biocompatibility.
• Chemical Research (R&D): A versatile reagent for constructing diverse heterocyclic compounds and complex molecular architectures in academic and industrial laboratories.
• Dye and Pigment Chemistry: Intermediate in the production of advanced colorants and functional dyes requiring specific sulfonated structures.

Basic Information

Product Name	4-(Isocyanatosulfonyl)-Anisole
CAS No.	7018-76-0
Molecular Formula	C8H7NO4S
Molecular Weight	213.21 g/mol
Synonyms	4-Methoxyphenylsulfonyl isocyanate; p-Anisylsulfonyl isocyanate; 4-Methoxybenzenesulfonyl isocyanate; 1-Isocyanato-4-methoxybenzene-1-sulfonyl; Anisole-4-sulfonyl isocyanate; 4-(Isocyanatosulphonyl)anisole; p-Methoxyphenylsulfonyl isocyanate
EINECS	Contact for details

Quality Control

Our 4-(Isocyanatosulfonyl)-Anisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.