Description

(-)-Norgestrel is a potent synthetic progestogen, a key active pharmaceutical ingredient (API) in hormonal contraceptives and hormone replacement therapies. Its high purity grade of 98% ensures reliable efficacy and safety for critical pharmaceutical formulations. This compound is essential for manufacturers in the pharmaceutical industry developing oral contraceptives, hormone-based treatments, and advanced drug delivery systems.

Application

• Active Pharmaceutical Ingredient (API): Primary component in oral contraceptive pills and other hormonal medications.
• Hormone Replacement Therapy (HRT): Used in formulations to manage menopausal symptoms and hormonal imbalances.
• Pharmaceutical Research & Development: Serves as a reference standard and key intermediate in developing new therapeutic agents.
• Veterinary Pharmaceuticals: Employed in hormonal treatments for animal health.
• Controlled-Release Drug Delivery Systems: A critical agent in the development of implants, patches, and other sustained-release formulations.

Basic Information

Product Name	(-)-Norgestrel
CAS No.	797-64-8
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	Levonorgestrel; D(-)-Norgestrel; 13β-Ethyl-17β-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one; 17α-Ethynyl-13β-ethyl-17β-hydroxygon-4-en-3-one; Wy-5104; NG; LNG; (-)-13β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one
EINECS	212-349-1

Quality Control

Our (-)-Norgestrel is manufactured under strict quality management systems, ensuring it meets the rigorous standards required for pharmaceutical actives. Each batch is tested for identity, purity, and impurities using validated analytical methods, including HPLC and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% min
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Loss on Drying	NMT 0.5%
Residue on Ignition	NMT 0.1%
Specific Rotation	-30° to -35° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.