Description

7-Aza-Spiro[3.5]Nonane is a versatile and high-value nitrogen-containing spirocyclic building block. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily used by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers seeking to incorporate complex, three-dimensional molecular scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and infectious diseases.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) by introducing conformational constraint and improving pharmacokinetic properties in lead optimization.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to construct molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in academia and industry exploring new chemical space and reaction methodologies.

Basic Information

Product Name	7-Aza-Spiro[3.5]Nonane
CAS No.	766-34-7
Molecular Formula	C8H15N
Molecular Weight	125.21 g/mol
Synonyms	7-Azaspiro[3.5]nonane; 1-Azaspiro[3.5]nonane; Azaspiro[3.5]nonane; 7-Aza-spiro[3.5]nonane; Spiro[3.5]nonan-7-amine (incorrect but common search); 7-Aza-spiro(3,5)nonane; 7-Azaniaspiro[3.5]nonane; 1-Aza-4-cyclohexylpyrrolidine (related structure).
EINECS	Contact for details

Quality Control

Our 7-Aza-Spiro[3.5]Nonane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development projects with material that meets the stringent standards required for pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere or desiccant.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.