Description

Dimethyl A-Bromoglutarate is a high-purity brominated ester compound, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in its reactive bromine and ester functionalities, enabling precise chemical transformations for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with glutaric acid backbones or those requiring bromo-alkylation steps.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bromine moiety facilitates specific coupling reactions.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules, including natural product analogs and functional materials.
• Peptide Mimetics & Modifications: Useful in medicinal chemistry for the design and synthesis of peptide analogs and prodrugs, leveraging the ester groups for further functionalization.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form new carbon-carbon bonds.
• Polymer Chemistry: Can serve as a monomer or modifier in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	Dimethyl A-Bromoglutarate
CAS No.	760-94-1
Molecular Formula	C7H11BrO4
Molecular Weight	239.06 g/mol
Synonyms	Dimethyl 2-Bromoglutarate; 2-Bromopentanedioic Acid Dimethyl Ester; Dimethyl 2-Bromopentanedioate; Bromoglutaric Acid Dimethyl Ester; α-Bromoglutaric Acid Dimethyl Ester; Pentanedioic acid, 2-bromo-, 1,5-dimethyl ester
EINECS	212-081-7

Quality Control

Our Dimethyl A-Bromoglutarate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area away from strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep the container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.