Description

3-Fluoropyruvic Acid Ethyl Ester is a high-value fluorinated building block essential for advanced organic synthesis. This compound is critical for introducing the fluoropyruvate moiety into target molecules, enabling the development of novel compounds with modified biological and physicochemical properties. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of fluorinated active pharmaceutical ingredients (APIs), particularly protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the creation of novel fluorinated herbicides and pesticides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Biochemical Research: Serves as a precursor for synthesizing fluorinated analogs of metabolic intermediates to study enzyme mechanisms and pathways.
• Peptide Mimetics: Employed in the synthesis of fluorinated amino acid derivatives and peptide analogs for drug discovery programs.
• Material Science Precursor: Utilized in the development of specialty polymers and advanced materials with unique surface properties.
• Cross-Coupling Reactions: Acts as an electrophile in various palladium-catalyzed cross-coupling reactions to construct complex fluorinated architectures.

Basic Information

Product Name	3-Fluoropyruvic Acid Ethyl Ester
CAS No.	760-10-1
Molecular Formula	C5H7FO3
Molecular Weight	134.10 g/mol
Synonyms	Ethyl 3-Fluoropyruvate; Ethyl 3-Fluoro-2-oxopropanoate; 3-Fluoro-2-oxopropanoic Acid Ethyl Ester; 3-Fluoropyruvic Acid Ethyl Ester; 2-Oxo-3-fluoropropionic Acid Ethyl Ester; Ethyl 3-Fluoropyruvate; 3-Fluoropyruvic Acid Ethyl Ester; Ethyl α-Fluoropyruvate
EINECS	212-076-8

Quality Control

Our 3-Fluoropyruvic Acid Ethyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.