Description

Quinine Benzoate is a pharmaceutical-grade salt formed from the alkaloid quinine and benzoic acid, offering enhanced stability and solubility. This compound is valued for its precise pharmacological activity and serves as a critical intermediate in the synthesis of specialized therapeutic agents. It is primarily required by manufacturers in the pharmaceutical, research, and fine chemical sectors for developing antipyretic and antimalarial formulations.

Application

• Pharmaceutical Intermediates: Key starting material in the synthesis of antimalarial and antipyretic APIs (Active Pharmaceutical Ingredients).
• Analytical Reference Standards: Used as a high-purity standard in HPLC and LC-MS for quality control and research quantification.
• Biochemical Research: Employed in pharmacological studies to investigate mechanisms of action related to fever reduction and parasite inhibition.
• Fine Chemical Synthesis: Serves as a chiral building block for the preparation of more complex, biologically active molecules.
• Veterinary Medicine: Component in formulations for treating specific parasitic infections in animals.

Basic Information

Product Name	Quinine Benzoate
CAS No.	750-88-9
Molecular Formula	C₂₆H₂₈N₂O₄
Molecular Weight	432.51 g/mol
Synonyms	Benzoic acid, compd. with quinine (1:1); Quinine monobenzoate; Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-, benzoate (salt); Quinine benzoate salt; NSC 199935; Quinine acid benzoate; Quinine (mono)benzoate
EINECS	212-028-9

Quality Control

Our Quinine Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) detailing results against relevant pharmacopoeial standards (such as USP/EP where applicable) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Loss on Drying	≤ 1.0%
Specific Rotation [α]²⁰D	-150° to -160° (c=1 in CHCl₃)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.