Description

Benzobarbital CAS NO 744-80-9 is a synthetic barbiturate derivative, a class of compounds historically significant for their central nervous system depressant properties. This compound serves as a crucial pharmaceutical intermediate and a reference standard in analytical and research settings. It is primarily required by pharmaceutical R&D laboratories, quality control departments, and academic institutions engaged in neuropharmacology and medicinal chemistry studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex barbiturate-based active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, GC, and other chromatographic analyses within pharmaceutical testing.
• Pharmacological Research: Employed in preclinical studies to investigate the structure-activity relationships (SAR) of barbiturates and their effects on GABA receptors.
• Forensic Science: Serves as a controlled substance standard for identification and quantification in forensic toxicology laboratories.
• Chemical Synthesis: Utilized in organic chemistry research for exploring novel synthetic pathways and creating derivative compounds.

Basic Information

Product Name	Benzobarbital
CAS No.	744-80-9
Molecular Formula	C12H12N2O3
Molecular Weight	232.24 g/mol
Synonyms	5-Benzyl-5-ethylbarbituric acid; Benzobarbitone; 5-Ethyl-5-benzylbarbituric acid; 5-Benzyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; NSC 3080; Benzyl ethyl barbituric acid; Ethylbenzylbarbituric acid
EINECS	212-047-5

Quality Control

Our Benzobarbital is produced and handled under strict quality management protocols. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, IR, and other relevant pharmacopeial tests. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	173 - 177 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.