Description

Thalidomide (+ And -) is a synthetic glutamic acid derivative with a complex and significant history in pharmaceutical research. This compound, provided as the racemic mixture, is a critical reference standard and a key intermediate in advanced biomedical studies. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and quality control departments for analytical and investigative purposes. The material is handled under strict ethical and regulatory frameworks for scientific advancement.

Application

• Pharmaceutical Reference Standard: Serves as a primary chemical standard for the calibration of analytical instruments (HPLC, GC-MS) and the validation of testing methods in quality control laboratories.
• Biomedical Research: Used in preclinical studies to investigate mechanisms of action, particularly in fields related to immunomodulation and angiogenesis, under controlled research protocols.
• Chemical Intermediate: Acts as a crucial building block in the synthetic pathway for developing novel analogs and derivatives for research purposes.
• Academic Research: Employed in university and institutional labs for educational and investigative projects concerning drug design, stereochemistry, and teratogenicity studies.
• Analytical Method Development: Essential for developing and optimizing chromatographic separation techniques for enantiomeric purity assessment.
• Regulatory Compliance Testing: Used to ensure analytical procedures meet the stringent requirements of regulatory bodies for related compound analysis.

Basic Information

Product Name	Thalidomide (+ And -)
CAS No.	731-40-8
Molecular Formula	C13H10N2O4
Molecular Weight	258.23 g/mol
Synonyms	Thalidomide (racemic); (±)-Thalidomide; α-Phthalimidoglutarimide; 2-(2,6-Dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione; N-Phthaloylglutamimide; Kevadon (historical brand name); Contergan (historical brand name); Sedalis (historical brand name)
EINECS	211-990-1

Quality Control

Our Thalidomide (+ And -) is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and composition. A detailed Certificate of Analysis (COA) is provided, which includes results from tests such as HPLC for assay and related substances, chiral purity analysis, and identification by IR spectroscopy. We adhere to relevant guidelines for research-grade chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture (50:50 ratio of enantiomers ± 2%)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.