Description

Methyl3-Nitro-4-(Trifluoromethoxy)Benzoate is a high-purity, synthetically valuable aromatic ester building block. This compound is critical for advanced organic synthesis, serving as a versatile intermediate for constructing complex molecules with specific functional group arrays. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients. Its unique trifluoromethoxy and nitro substituents make it a key precursor for introducing these pharmacologically and agrochemically important motifs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethoxy-phenyl core for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the nitro and trifluoromethoxy groups contribute to biological activity.
• Material Science Precursor: Serves as a monomer or intermediate for synthesizing specialty polymers and advanced organic materials with specific electronic or surface properties.
• Ligand and Catalyst Development: Employed in organic chemistry research for the creation of novel ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: An important substrate for investigating reactions involving fluorinated aromatic systems and for introducing fluorine-containing groups into target molecules.

Basic Information

Product Name	Methyl3-Nitro-4-(Trifluoromethoxy)Benzoate
CAS No.	728-54-1
Molecular Formula	C9H6F3NO5
Molecular Weight	265.15 g/mol
Synonyms	Methyl 3-nitro-4-(trifluoromethoxy)benzoate; Benzoic acid, 3-nitro-4-(trifluoromethoxy)-, methyl ester; 4-(Trifluoromethoxy)-3-nitrobenzoic acid methyl ester; Methyl 4-(trifluoromethoxy)-3-nitrobenzoate; 3-Nitro-4-trifluoromethoxybenzoic acid methyl ester; Methyl ester of 3-nitro-4-(trifluoromethoxy)benzoic acid
EINECS	Contact for details

Quality Control

Our Methyl3-Nitro-4-(Trifluoromethoxy)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.