Description

n-Methylcyclobarbital is a synthetic barbiturate derivative with the CAS registry number 726-78-3. This compound is a key intermediate in pharmaceutical research and development, particularly in the study of central nervous system (CNS) agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the synthesis of specialized therapeutic compounds and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of novel barbiturate-based therapeutic agents.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.
• Biochemical Research: Employed in pharmacological studies to investigate the structure-activity relationships (SAR) of sedative-hypnotic compounds.
• Chemical Synthesis: Serves as a specialized precursor for the preparation of more complex, target-specific molecules in medicinal chemistry.
• Academic Research: Utilized in university and institutional labs for advanced studies in neuropharmacology and organic synthesis.

Basic Information

Product Name	n-Methylcyclobarbital
CAS No.	726-78-3
Molecular Formula	C13H18N2O3
Molecular Weight	250.29 g/mol
Synonyms	5-(1-Cyclohexen-1-yl)-1-methyl-5-(2-pentenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 1-Methyl-5-(1-cyclohexen-1-yl)-5-(2-pentenyl)barbituric Acid; Methylcyclobarbital; NSC 523767; Cyclobarbital Methyl Derivative
EINECS	Contact for details

Quality Control

Our n-Methylcyclobarbital is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and GC, to ensure it meets exacting standards for research use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.