Description

1,3-Di-p-Tolylcarbodiimide is a versatile carbodiimide compound primarily used as a zero-length crosslinking and coupling agent in organic synthesis. Its value lies in its ability to facilitate the formation of amide bonds under mild conditions, making it a critical reagent for peptide synthesis and polymer modification. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries seeking efficient and reliable condensation reactions.

Application

• Peptide Synthesis: Acts as a dehydrating agent for the condensation of amino acids, enabling the formation of peptide bonds.
• Polymer Modification: Used to crosslink polymers containing carboxyl or amine groups, enhancing material properties like stability and mechanical strength.
• Bioconjugation: Facilitates the coupling of proteins, antibodies, or other biomolecules to labels, solid supports, or drugs.
• Agrochemical Intermediate: Serves as a key building block in the synthesis of certain herbicides, fungicides, and plant growth regulators.
• Pharmaceutical Intermediate: Employed in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs requiring amide linkage.
• Adhesive & Coating Formulations: Imparts improved adhesion and durability when used as a crosslinker in specialty coatings and adhesive systems.

Basic Information

Product Name	1,3-Di-p-Tolylcarbodiimide
CAS No.	726-42-1
Molecular Formula	C₁₇H₁₈N₂
Molecular Weight	250.34 g/mol
Synonyms	Di-p-tolylcarbodiimide; 1,3-Bis(4-methylphenyl)carbodiimide; p-Tolylcarbodiimide; DTC; Bis(4-methylphenyl)carbodiimide; N,N'-Di-p-tolylcarbodiimide; 4,4'-Dimethylphenylcarbodiimide; Carbodiimide, di-p-tolyl-
EINECS	211-974-8

Quality Control

Our 1,3-Di-p-Tolylcarbodiimide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.