Description

Methyl 3-Amino-4-(Trifluoromethoxy)Benzoate is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters because its unique trifluoromethoxy and amino ester functionalities make it a versatile intermediate for creating molecules with enhanced biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used to construct advanced herbicides and pesticides, where the trifluoromethoxy group can improve lipophilicity and biological performance.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., Buchwald-Hartwig amination) and cyclization reactions to create complex heterocycles.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to its reactive amino group.

Basic Information

Product Name	Methyl 3-Amino-4-(Trifluoromethoxy)Benzoate
CAS No.	721-09-5
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	3-Amino-4-(trifluoromethoxy)benzoic acid methyl ester; Methyl 3-amino-α,α,α-trifluoro-p-anisate; Benzoic acid, 3-amino-4-(trifluoromethoxy)-, methyl ester; Methyl 3-amino-4-trifluoromethoxybenzoate; 721-09-5; 3-Amino-4-trifluoromethoxy methyl benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-4-(Trifluoromethoxy)Benzoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by modern analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.