Description

Norhexobarbital CAS NO 718-67-2 is a synthetic barbiturate derivative, a class of compounds historically significant for their central nervous system depressant properties. Its precise chemical structure makes it a valuable reference standard and a key intermediate in pharmaceutical research and development. This compound is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in method development, quality control, and the synthesis of specialized chemical entities.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of barbiturate-related compounds in research and quality control laboratories.
• Chemical Intermediate: Serves as a crucial building block in the organic synthesis of more complex pharmaceutical molecules and novel chemical entities.
• Analytical Research: Employed in method development and validation for chromatographic techniques (HPLC, GC) and spectroscopic analysis in forensic and clinical toxicology.
• Biochemical Studies: Used in pharmacological research to study the structure-activity relationships (SAR) of barbiturates and their interaction with biological targets.
• Impurity Standard: Acts as a certified impurity standard to monitor and control related substances in the manufacture of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Norhexobarbital
CAS No.	718-67-2
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	5-Ethyl-5-(1-cyclohexen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-(1-cyclohexenyl)barbituric acid; 5-(1-Cyclohexen-1-yl)-5-ethylbarbituric acid; NSC 7424; Nor-Hexobarbital; Norhexobarbitone; Hexobarbital Impurity
EINECS	Contact for details

Quality Control

Our Norhexobarbital is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets stringent specifications for research use. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.