Description

Diethyl cis-Cyclopropane-1,2-Dicarboxylate is a high-purity, versatile diester building block essential for advanced organic synthesis. Its rigid cis-cyclopropane scaffold and reactive ester groups make it a critical intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of cyclopropane-containing drug candidates, including protease inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclopropane ring enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and monomers with unique thermal and mechanical properties.
• Organic Synthesis Building Block: Utilized in Diels-Alder reactions, ring-opening transformations, and other C-C bond-forming processes to introduce the cyclopropane moiety.
• Flavor and Fragrance Industry: Acts as an intermediate for synthesizing certain aroma chemicals with complex, stereodefined structures.

Basic Information

Product Name	Diethyl cis-Cyclopropane-1,2-Dicarboxylate
CAS No.	710-43-0
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	cis-1,2-Cyclopropanedicarboxylic Acid Diethyl Ester; Diethyl (1R,2S)-1,2-Cyclopropanedicarboxylate; Diethyl cis-1,2-Cyclopropanedicarboxylate; Ethyl cis-Cyclopropane-1,2-Dicarboxylate; (+/-)-Diethyl Cyclopropane-1,2-Dicarboxylate; 1,2-Cyclopropanedicarboxylic Acid, Diethyl Ester, cis-; Diethyl Cyclopropane-cis-1,2-Dicarboxylate
EINECS	211-916-8

Quality Control

Our Diethyl cis-Cyclopropane-1,2-Dicarboxylate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.