Description

8-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione is a specialized heterocyclic compound featuring a unique spirocyclic structure, making it a valuable synthetic intermediate and building block in advanced organic chemistry. This compound is critical for research and development in the pharmaceutical sector, where its structural motif is leveraged to create novel molecular entities. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring spirocyclic scaffolds for enhanced bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, where the diazaspirodecane core can contribute to unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor or framework for creating specialized ligands used in asymmetric catalysis and metal-organic complexes.
• Material Science: Investigated as a monomer or additive for producing polymers with specific thermal or mechanical properties.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in heterocyclic and spiro compound chemistry.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) producing bespoke chemicals for client projects.

Basic Information

Product Name	8-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione
CAS No.	707-17-5
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	8-Methyl-1,3-diazaspiro[4.5]decane-2,4-dione; 1,3-Diazaspiro[4.5]decane-2,4-dione, 8-methyl-; 8-Methylspiro[imidazolidine-4,1'-cyclohexane]-2,5-dione; NSC 102627; 8-Methyl-1,3-diazaspiro[4.5]decan-2,4-dione; 8-Methyl-2,4-imidazolidinedione, hexahydro-1H-spiro[imidazole-4,1'-cyclohexane]-; Spiro[imidazolidine-4,1'-cyclohexane]-2,5-dione, 8-methyl-
EINECS	Contact for details

Quality Control

Our 8-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.