Description

3-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione is a versatile spirocyclic hydantoin derivative, a key heterocyclic building block valued for its constrained molecular geometry and functional group reactivity. This compound is essential for advanced research and development in medicinal chemistry, where it serves as a privileged scaffold for designing novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for applications in drug discovery, material science, and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its spirocyclic structure for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor or core structure for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Investigated for the synthesis of novel polymers, dendrimers, and organic electronic materials due to its rigid, three-dimensional shape.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Fine Chemical Production: Acts as an advanced intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	3-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione
CAS No.	707-09-5
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	1-Methylspirohydantoin; 3-Methyl-1,3-diazaspiro[4.5]decane-2,4-dione; 1-Methyl-1-azaspiro[4.5]decane-2,4-dione; Spirohydantoin, 1-methyl-; 1-Methylspiro[imidazolidine-4,1'-cyclohexane]-2,5-dione; NSC 51143; 1-Methyl-1-azaspiro[4.5]decan-2,4-dione
EINECS	211-906-1

Quality Control

Our 3-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.