Description

2-Trimethylsilylanisole is a versatile organosilicon compound, specifically a silylated anisole derivative, valued for its role as a protective group and synthetic intermediate in advanced organic synthesis. Its primary commercial value lies in its ability to act as a stable, silicon-based precursor or reagent, facilitating complex chemical transformations with high selectivity and yield. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for producing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, particularly where the anisole moiety needs protection from harsh reaction conditions.
• Agrochemical Synthesis: Serves as a key building block in the production of herbicides, fungicides, and other crop protection agents.
• Material Science Precursor: Employed in the development of silicon-containing polymers, resins, and advanced coatings with tailored properties.
• Organic Synthesis Reagent: Functions as a silylating agent to introduce the trimethylsilyl (TMS) group, protecting hydroxyl or other sensitive functional groups during multi-step syntheses.
• Liquid Crystal & OLED Material Research: Acts as a starting material or intermediate in the creation of organic semiconductors and display technologies.
• Flavor & Fragrance Industry: Utilized in the synthesis of specific aromatic compounds where the methoxybenzene structure is required.

Basic Information

Product Name	2-Trimethylsilylanisole
CAS No.	704-43-8
Molecular Formula	C10H16OSi
Molecular Weight	180.32 g/mol
Synonyms	2-(Trimethylsilyl)anisole; 1-Methoxy-2-(trimethylsilyl)benzene; o-(Trimethylsilyl)anisole; Anisole, 2-(trimethylsilyl)-; 2-Methoxyphenyltrimethylsilane; Trimethyl(2-methoxyphenyl)silane; o-Methoxyphenyltrimethylsilane
EINECS	Contact for details

Quality Control

Our 2-Trimethylsilylanisole is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chromatography and spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.