Description

Medroxyprogesterone Acetate CAS NO 71-58-9 is a synthetic progestin, a derivative of progesterone, widely recognized for its potent hormonal activity and stability. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of a range of therapeutic formulations. It is an essential raw material for pharmaceutical manufacturers developing hormone replacement therapies, contraceptive products, and treatments for specific gynecological and oncological conditions.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable and oral contraceptive formulations.
• Hormone Replacement Therapy (HRT): Used in combination with estrogens to manage menopausal symptoms and prevent endometrial hyperplasia.
• Gynecological Treatments: Employed in the management of secondary amenorrhea, abnormal uterine bleeding, and endometriosis.
• Oncological Applications: Utilized as a component in certain palliative treatment regimens for advanced endometrial and renal carcinoma.
• Veterinary Medicine: Applied in estrus synchronization and the treatment of reproductive disorders in animals.
• Research & Development: Serves as a key reference standard and intermediate in biochemical research and the development of new hormonal agents.

Basic Information

Product Name	Medroxyprogesterone Acetate
CAS No.	71-58-9
Molecular Formula	C24H34O4
Molecular Weight	386.53 g/mol
Synonyms	17α-Hydroxy-6α-methylprogesterone acetate; 6α-Methyl-17α-acetoxyprogesterone; Depo-Provera (brand name); MPA; Farlutal; Provera; Gestapuran; Perlutex; 6α-Methyl-17α-hydroxyprogesterone acetate
EINECS	200-756-7

Quality Control

Our Medroxyprogesterone Acetate is manufactured under strict quality systems to meet the rigorous standards of the global pharmaceutical industry. We offer grades compliant with major pharmacopoeias, including USP and EP. Every batch undergoes comprehensive analytical testing, including identity, purity, and impurity profile verification. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in its original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Specific Rotation	+53° to +59° (c = 1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.