Description

Carbamic Acid, [(1R,3S)-1-Ethynyl-3-Hydroxybutyl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in antiviral and oncology research.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the study and development of new catalytic systems.
• Peptidomimetics & Prodrug Development: The carbamate and hydroxyl functionalities make it valuable for designing peptide analogs and prodrug candidates.
• Material Science Research: Potential monomer or building block for specialty polymers with specific chiral properties.
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Carbamic Acid, [(1R,3S)-1-Ethynyl-3-Hydroxybutyl]-, 1,1-Dimethylethyl Ester
CAS No.	697752-27-5
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	(1R,3S)-1-Ethynyl-3-hydroxybutyl carbamic acid tert-butyl ester; tert-Butyl N-[(1R,3S)-1-ethynyl-3-hydroxybutyl]carbamate; (3S,5R)-5-Ethynyl-3-hydroxytetrahydro-2H-pyran-2-one tert-butyl carbamate derivative; BOC-Protected (1R,3S)-1-ethynyl-3-hydroxybutylamine; Chiral ethynyl hydroxybutyl BOC-carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1R,3S)-1-Ethynyl-3-Hydroxybutyl]-, 1,1-Dimethylethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.