Description

2-Chloro-6-Methylpyridine-4-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules and bioconjugates for studying biological pathways and target engagement.
• Catalyst & Ligand Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	2-Chloro-6-Methylpyridine-4-Boronic Acid Pinacol Ester
CAS No.	697739-22-3
Molecular Formula	C₁₂H₁₇BClNO₂
Molecular Weight	253.53 g/mol
Synonyms	2-Chloro-6-methylpyridine-4-boronic acid pinacol ester; (2-Chloro-6-methylpyridin-4-yl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2-chloro-6-methylpyridin-4-yl)-1,3,2-dioxaborolane; 2-Chloro-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Chloro-6-methylpyridine-4-boronic acid, pinacol ester; Boronic acid, B-(2-chloro-6-methyl-4-pyridinyl)-, 1,1-dimethylethyl ester; CAS 697739-22-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methylpyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with full specification data are provided for all shipments, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.