Description

2-Chloro-4-(3-Trifluoromethylphenyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethylphenyl and chloropyridine moieties. This compound matters as a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and optimizing synthetic routes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and trifluoromethyl groups.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex, functionalized molecules for various applications.
• Ligand Synthesis: Useful for preparing novel ligands in catalysis and coordination chemistry due to the nitrogen donor atom and aromatic system.

Basic Information

Product Name	2-Chloro-4-(3-Trifluoromethylphenyl)Pyridine
CAS No.	697739-20-1
Molecular Formula	C12H7ClF3N
Molecular Weight	257.64 g/mol
Synonyms	2-Chloro-4-[3-(trifluoromethyl)phenyl]pyridine; 4-(3-Trifluoromethylphenyl)-2-chloropyridine; 2-Chloro-4-(3-trifluoromethylphenyl)pyridine; 2-Chloro-4-(α,α,α-trifluoro-m-tolyl)pyridine; 2-Chloro-4-(m-trifluoromethylphenyl)pyridine; 2-Chloro-4-(3-(trifluoromethyl)phenyl)pyridine; 2-Chloro-4-(3-trifluoromethyl-phenyl)-pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3-Trifluoromethylphenyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.