Description

2-Chloro-4-(4-Trifluoromethoxyphenyl)Pyridine is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its molecular structure, featuring a chloropyridine core linked to a trifluoromethoxyphenyl group, makes it a critical synthon for constructing complex molecules with tailored biological activity. This compound is primarily sought after by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and insecticides, where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized ligands and organic frameworks in advanced material development.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	2-Chloro-4-(4-Trifluoromethoxyphenyl)Pyridine
CAS No.	697739-19-8
Molecular Formula	C12H7ClF3NO
Molecular Weight	273.64 g/mol
Synonyms	2-Chloro-4-[4-(trifluoromethoxy)phenyl]pyridine; 4-(4-Trifluoromethoxyphenyl)-2-chloropyridine; 2-Chloro-4-(4-trifluoromethoxyphenyl)pyridine; 2-Chloro-4-(α,α,α-trifluoro-p-methoxyphenyl)pyridine; Pyridine, 2-chloro-4-[4-(trifluoromethoxy)phenyl]-; CAS 697739-19-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(4-Trifluoromethoxyphenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.