Description

1-(4-Fluorophenyl)Piperazin-2-One Hydrochloride is a high-purity, synthetically derived organic compound belonging to the piperazine class, serving as a crucial building block in advanced pharmaceutical research and development. Its core value lies in its role as a versatile intermediate for synthesizing novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new therapeutic agents, especially for CNS-targeted drugs.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for candidate drugs.
• Reference Standard: Serves as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Research: Potential use in probing biological pathways and enzyme interactions due to its specific pharmacophore.

Basic Information

Item	Detail
Product Name	1-(4-Fluorophenyl)Piperazin-2-One Hydrochloride
CAS No.	697305-48-9
Molecular Formula	C10H12FN3O·HCl
Molecular Weight	245.68 g/mol
Synonyms	1-(4-Fluorophenyl)-2-piperazinone hydrochloride; 4-Fluorophenylpiperazin-2-one HCl; 2-Piperazinone, 1-(4-fluorophenyl)-, hydrochloride; 1-(p-Fluorophenyl)piperazin-2-one hydrochloride; 697305-48-9 (CAS); 1-(4-Fluorophenyl)-1,4-diazepan-2-one hydrochloride; 1-(4-Fluorophenyl)-2-oxopiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)Piperazin-2-One Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.